Appeal No. 2005-1344 Page 3
Application No. 08/468,610
an aqueous medium binds to the resin when the aqueous medium
has either a high or a low ionic strength.
The references relied upon by the examiner are:
Economy et al. (Economy) 3,835,072 Sep. 10, 1974
Jones et al. (Jones) 4,154,676 May 15, 1979
Hancock et al. (Hancock) 4,401,629 Aug. 30, 1983
Bruegger 4,810,391 Mar. 7, 1989
Iimuro et al. (Iimuro) 4,950,807 Aug. 21, 1990
Tokuyama JP 60-137441 Jul. 22, 1985
(PTO 04-4920 translation relied upon)
Kondo et al. (Kondo) JP 61-033130 Feb. 17, 1986
(PTO 04-4918 translation relied upon)
Kitamura et al. (Kitamura) JP 01-211543 Aug. 24, 1989
(PTO 04-4919 translation relied upon)
Topp et al., (Topp), “Properties of Ion-Exchange Resins in Relation to their
Structure. Part 1. Titration Curves,” J. Chem. Soc., pp. 3299-3303 (1949)
Boardman et al., (Boardman) “Separation of Neutral Proteins on Ion-Exchange
Resins,” Nature, Vol. 171, pp. 208-210 (1953)
Kitchener, “Properties and Behavior, 5. Effect of pH on Exchange Equilibria” in
Ion Exchangers in Organic and Biochemistry, pp. 63-65 (Calvin Calmon et al.,
eds., Interscience Publishers, Inc., New York, 1957)
Guthrie, “Ion Exchangers of Plant Origin, and Use of Resins in Plant Chemistry”
in Ion Exchangers in Organic and Biochemistry, pp. 558-559 (Calvin Calmon et
al., eds., Interscience Publishers, Inc., New York, 1957)
(Kunin), “Cation Exchange Resin Characteristics” in Ion Exchange Resins, pp.
34-39 (Robert Kunin ed., John Wiley & Sons, Inc., New York, 1958)
Sasaki et al. (Sasaki I) “Hydrophobic-Ionic Chromatography, Its Application to
Purification of Porcine Pancreas Enzymes,” J. Biochem., Vol. 86, pp. 1537-1548
(1979)
Sasaki et al. (Sasaki II) “Hydrophobic-Ionic Chromatography, Its Application to
Microbial Glucose Oxidase, Hyaluronidase, Cholesterol Oxidase, and Cholesterol
Esterase,” J. Biochem., Vol. 91, pp. 1555-1561 (1982)
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