Appeal No. 2005-2235 Page 2 Application No. 09/038,894 32. A method, comprising: assessing cell activation in a subject; and, if elevated, administering activation lowering therapy, thereby preventing a disease or disorder or reducing the risk of a poor outcome of a treatment of a disease or disorder. The examiner does not rely on prior art. GROUNDS OF REJECTION Claims 10-18, 32-36, 38, 41 and 42 stand rejected under 35 U.S.C. § 112, second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which appellants regard as the invention. Claims 32-36, 38, 41 and 42 stand rejected under 35 U.S.C. § 112, first paragraph, as being based on an insufficient disclosure to support or enable the claimed invention. Claims 10-18, 32-36, 38, 41 and 42 stand rejected under 35 U.S.C. § 112, first paragraph, as being based on an insufficient disclosure to support or enable the full scope of the claimed invention. We reverse. DISCUSSION Definiteness: Claims 10-18, 32-36, 38, 41 and 42 stand rejected under 35 U.S.C. § 112, second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which appellants regard as the invention. According to the examiner (Answer, pages 6-7), the claims are unclear with regard to the phrases “administering activation lowering therapy” andPage: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007