Ex Parte Afriat - Page 5


                Appeal No.  2005-2743                                                   Page 5                 
                Application No.  09/847,388                                                                    
                As appellant points out (Brief, page 4), “Sebillotte-Amaud’s solution to this                  
                problem is a [stable] gel composition containing a hydrophilic medium or carrier,              
                not a conventional oil-containing composition such as an emulsion.”  Based on                  
                this analysis of the references, appellant reasons (id., emphasis removed),                    
                      [g]iven that Sebillotte-Arnaud found that his active agents were                         
                      stable in a gel containing a hydrophilic carrier but were not stable in                  
                      other types of compositions, one skilled in the art would not have                       
                      been motivated to use such active agents in a composition which                          
                      did not possess a hydrophilic carrier because no expectation would                       
                      have existed that the resulting active agent-containing composition                      
                      would be stable.                                                                         
                      In response, the examiner argues (Answer, page 5), “one of ordinary skill                
                would be motivated to add other active agents [to Castro’s composition] to obtain              
                a dual effect.”  While this may be true, we fail to understand why a person of                 
                ordinary skill in the art would select an active agent, such as those taught by                
                Sebillotte-Amaud, which would be difficult, or impossible to incorporate into the              
                emulsion taught by Castro.  Further, we recognize the examiner’s argument                      
                (Answer, bridging paragraph, pages 5-6), “[r]etinols[, as taught by Castro] and                
                azelaic acid[, as set forth in appellant’s claims], although chemically different              
                agents, are known in the art for combating acne and related skin disorders …                   
                [c]learly one of ordinary skill in the art would be able to substitute one for the             
                other.”  However, while Castro teaches retinols, retinols are not included in                  
                appellant’s claimed listing of active agents.  In addition, while appellant’s claims           
                identify azelaic acid as an active agent, neither Castro nor Sebillotte-Amaud                  
                teach azelaic acid.  Accordingly, we are not persuaded by the examiner’s                       
                argument.                                                                                      







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