Appeal No. 2006-0258 Page 18 Application No. 09/755,747 and 76 under 35 U.S.C. § 103(a) as being unpatentable over the combination of Stimpson and Wittwer. The combination of Stimpson, Wittwer and Heller: Claims 1-5, 7, 8, 10-18, 20, 21, 23-31, 33, 34, 36-44, 46, 47, 49-52, and 67-76 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Stimpson, Wittwer and Heller. The examiner relies on the combination of Stimpson and Wittwer as set forth above. According to the examiner (Answer, page 9), the combination of Stimpson and Wittwer “do not teach immobilization of the oligonucleotide using biotin-streptavidin.” To make up for this deficiency the examiner relies on Heller. According to the examiner (id.), “Heller teaches immobilization of oligonucleotides to arrays using biotin-streptavidin for nucleic acid detection assays.” Heller, however, does not make up for the deficiencies in the combination of Stimpson in view of Wittwer. Accordingly, we reverse the rejection of claims 1-5, 7, 8, 10-18, 20, 21, 23- 31, 33, 34, 36-44, 46, 47, 49-52, and 67-76 under 35 U.S.C. § 103(a) as being unpatentable over the combination of Stimpson, Wittwer and Heller. The combination of Stimpson, Wittwer and Konrad: Claims 1-6, 8-19, 21-32, 34-45, 47-52, 67-71, 73, 74, and 76 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Stimpson, Wittwer and Konrad.Page: Previous 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 NextLast modified: November 3, 2007