Appeal No. 2006-0730 Page 5 Application No. 10/164,863 requires only a disclosure that conveys with reasonable clarity to those skilled in the art that the inventor was in possession of the invention. See id. In this case, the examiner has not adequately explained why the description provided by the specification would not be considered sufficient by those skilled in the art. We therefore reverse the rejection based on the written description provision of 35 U.S.C. § 112, first paragraph. Enablement: According to the examiner (Answer, page 3), appellants’ specification provides an enabling disclosure of “altering fertility in female mice by knocking out the SR-BI gene. . . .” The examiner finds, however, appellants’ specification fails to enable “any method of treating infertility or treating any and all reproductive disorders by altering lipoprotein, LDL, or HDL transfer, or cholesterol levels in a mammal.” Id. According to the examiner (id.), appellants “provided no guidance and working examples of any compounds which act via SR-BI to alter fertility . . . other than those in knockout infertile female mice.” In response, appellants assert (Brief, page 11), “[a]s demonstrated by the examples at page 10, administering probucol to female mice that are deficient in SR-BI, and characterized by abnormal lipid levels restores their fertility. As discussed at page 28 of the application, the results prove that it is the abnormal lipid levels that cause the infertility.” The examiner provides no response to these arguments. As we understand the examiner’s arguments, it appears that the examiner’s basis for maintaining the rejection is his unsupported premise thatPage: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007