Ex Parte Ghosh et al - Page 5


                Appeal No.  2006-1021                                                   Page 5                
                Application No.  09/851,882                                                                   
                used for dry skin treatment.”  Answer, bridging sentence, pages 4-5.  In addition,            
                the examiner asserts (Answer, page 5),                                                        
                             [i]t would have been further obvious to one having ordinary                      
                      skill in the art at the time the invention was made to have modified                    
                      the Hoppe invention by adding urea as motivated by Raab because                         
                      of an expectation of successfully producing a topical composition                       
                      for treating skin disorders including senile xerosis[ ]4, with enhanced                 
                      moisturizing property and improved pharmaceutical effects of other                      
                      skin care actives.                                                                      
                Claim 1:                                                                                      
                      In response, appellants assert (Brief, page 6), “Hoppe does not teach or                
                suggest combining urea with any of the active compounds described therein, and                
                much less combining urea with coenzyme Q[-]10 specifically in a ratio of                      
                from about 6:1 to about 10:1 (wt./wt.) as required . . .” by claim 1.  Similarly,             
                appellants assert (id.), “Raab fails to teach or suggest adding coenzyme Q[-]10,              
                and much less combining urea and conenzyme Q[-]10 in a ratio of from about 6:1                
                to about 10:1 (wt./wt.) as required . . .” by claim 1.                                        
                      On reflection, we find the weight of the evidence favors the examiner.                  
                Hoppe discloses compositions that comprise coenzyme Q-10.  See e.g., Hoppe,                   
                column 7, Example III.  According to Hoppe, these compositions are useful for                 
                the treatment of aging skin (column 1, lines 4-8), and more particularly the                  
                treatment of “senile xerosis,” which is characterized by, inter alia dryness,                 
                roughness and itching of the skin (column 1, lines 8-17).  According to Hoppe                 
                (column 1, lines 55-58), “coenzyme Q-10 has an important function in the                      
                prevention of skin damage due to UV radiation and the prevention of aging of the              

                                                                                                              
                4 As taught by Hoppe.  Hoppe, column 1, lines 8-18.                                           





Page:  Previous  1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  Next 

Last modified: November 3, 2007