Appeal No. 2006-2248 Application No. 10/158,618 [I]t would have been obvious to one of ordinary skill in the art at the time the invention was made to prepare [Granger’s example 4] and add the specific fatty alcohol ester [octyl hydroxyl stearate] expecting beneficial effect, i.e. the compositions [would] exhibit better emolliency. 29. In due course, Applicants filed an amendment responding to the Examiner's first Office action. 30. As shown in Appendix 2 of this opinion, the amendment: (1) added new claim 11 and (2) amended claims 1 and 5, 31. New independent claim 11 covers a very specific embodiment of the compounds covered by claim 1. After entry of the amendment, the application claims were 1-11. 32. In the amendment, Applicants stated as follows: Applicant’s invention is directed to retinoid compositions which have a low irritation profile. As amended, Applicant’s invention claims a retinoid composition having a pH from about 4 to about 7. Felty neither teaches or suggests a retinoid composition having a pH from about 4 to about 7 or a retinoid composition which have a low irritation profile (the bottom of page 6 and top of page 7). 33. In the amendment, Applicants also stated as follows: Granger neither teaches nor suggests a retinoid composition having a specific pH range (page 7). - 10 -Page: Previous 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 NextLast modified: November 3, 2007