Appeal No. 2006-2248 Application No. 10/158,618 irritating ingredient, thus increasing the amount of its irritation-producing effects. Thus, glycerin should be present in the composition in a low penetration-enhancing effective amount (col. 7, lines 55-65). 13. A branched-chain fatty alcohol ester such as octyl hydroxy stearate may also contribute to the mildness of the compositions of this invention. Other branched-chain fatty esters may be useful in mitigating the irritating effects of the compositions of this invention (col. 8, lines 7-11). 14. Preferably, the inclusion of irritating compounds should be avoided. For example, butylene glycol is potentially irritating and may cause additional irritation in the type of formulations of this invention. Other potentially irritating compounds include soaps, amine-based compounds, surfactants, certain sunscreen active ingredients and compounds which cause the pH of the composition to become either extremely acidic or extremely basic (col. 7, line 66, to col. 8, line 6). 15. As shown herein at Appendix 6, Example 11 (col. 14, lines 25- 54) is the closest disclosed cosmetic composition to the composition claimed in - 7 -Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007