Ex Parte Bates et al - Page 3


                    Appeal No.  2006-2587                                                                   Page 3                      
                    Application No.  09/879,710                                                                                         
                    different reason in the reference, it would have been inherent to the process of                                    
                    Meisner that nitric oxide synthesis is inhibited since the steps of the processes                                   
                    (Meisner and the instant application) are the same.”                                                                
                           In response, appellants point out that the claims on appeal use the                                          
                    transitional phrase “consisting essentially of.”  Brief, page 4.  In this regard, we                                
                    note, “‘[c]onsisting essentially of’ is a transition phrase commonly used to signal a                               
                    partially open claim in a patent. . . .  By using the term ‘consisting essentially of,’                             
                    the drafter signals that the invention necessarily includes the listed ingredients                                  
                    and is open to unlisted ingredients that do not materially affect the basic and                                     
                    novel properties of the invention.”  PPG Indus. Inc. v. Guardian Indus. Corp,                                       
                    156 F.3d 1351, 1354, 48 USPQ2d 1351, 1353-54 (Fed. Cir. 1998).                                                      
                           According to appellants (Brief, page 4), Meisner’s composition requires                                      
                    four ingredients, one of which is “a precursor or stimulant of epinephrine or nor-                                  
                    epinephrine production selected from tyrosine, and phenylalanine. . . .”  In this                                   
                    regard appellants point out (Brief, page 5),                                                                        
                                    At the time of filing of the present application, current                                           
                           treatments options for hypotension or septic shock have been                                                 
                           limited to vasoconstricting agents that have many deleterious side                                           
                           effects that limit their therapeutic usage. (Spec. p. 2, lines 11-16).                                       
                           Therefore, a primary goal of the present invention was the                                                   
                           development of effective pharmacological treatments to counteract                                            
                           hypotension and shock without the deleterious side effects                                                   
                           associated with the use of vasoconstricting agents. (Spec. p. 2,                                             
                           lines 11-19).                                                                                                
                    According to appellants (Brief, page 6, emphasis removed),” “[e]phinephrine and                                     
                    norepinephrine are well known . . . potent vasocinstricting agents.”  Accordingly,                                  
                    appellants assert that adding a precursor or stimulant of epinephrine or                                            







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