Ex Parte Bates et al - Page 6


                    Appeal No.  2006-2587                                                                   Page 6                      
                    Application No.  09/879,710                                                                                         

                    Obviousness:                                                                                                        
                            The examiner relies on Meisner as discussed above.  The examiner                                            
                    notes, however, that Meisner does not teach that the S-alkylthiol is administered                                   
                    intravenously (see e.g., appellants’ claim 7), or is selected from the group                                        
                    consisting of, inter alia, S-methyl-L-cysteine (see e.g., appellants’ claim 3).                                     
                            To make up for these deficiencies, the examiner relies on Joullié to teach                                  
                    that S-methyl cysteine is well known to be injected into an animal for therapeutic                                  
                    purposes, and Chem. Abst. to teach that S-methylcysteine and S-methyl-L-                                            
                    cysteine are indeed the same compound.  However, upon careful review of these                                       
                    documents, we find ourselves in agreement with appellants in that neither                                           
                    reference makes up for the deficiency in Meisner, whose composition requires                                        
                    the presence of a precursor or stimulant of epinephrine or nor-epinephrine                                          
                    production selected from tyrosine, and phenylalanine.                                                               
                            Accordingly, we reverse the rejection of claims 2-8 and 10 under                                            
                    35 U.S.C. § 103 as being unpatentable over the combination of Meisner, Joullié                                      
                    and Chem. Abst.                                                                                                     


                                                          OTHER ISSUES                                                                  
                            Upon consideration of the evidence of record, we note that Joullié teaches                                  
                    pharmaceutical compositions comprising S-methylcysteine, which are                                                  
                    administered orally and intravenously.  See e.g., the LJ 1061 compositions at                                       
                    column 11, lines 7-45.  According to Joullié these compositions “may be                                             
                                                                                                                                        
                    1 According to Joullié (column 10, line 32), LJ 106 is S-methylcysteine.                                            





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