Ex Parte Ascione et al - Page 6

                 Appeal 2006-2632                                                                                       
                 Application 09/881,807                                                                                 

                 to one of ordinary skill in the art that he should make the claimed                                    
                 composition or device, or carry out the claimed process; and (2) whether the                           
                 prior art would also have revealed that in so making or carrying out, one of                           
                 ordinary skill would have a reasonable expectation of success.                                         
                 In re Vaeck, 947 F.2d 488, 493, 20 USPQ2d 1438, 1442 (Fed. Cir. 1991).                                 
                 Both the suggestion and the reasonable expectation of success “must be                                 
                 founded in the prior art, not in the applicant's disclosure.” Id.  In this case,                       
                 the Examiner has explained why one of ordinary skill would have reasonable                             
                 expectation of success (factor (2)), but has failed to provide a detailed                              
                 analysis of the prior art and reasons why one of ordinary skill in the art                             
                 would have possessed the knowledge and motivation to make the                                          
                 combination recited in the claims (factor (1)).  When the Examiner does not                            
                 explain the motivation, suggestion or teaching that would have led the                                 
                 skilled artisan to the claimed combination, there is an inference that the                             
                 Examiner relied on hindsight to conclude that the invention was obvious.                               
                 See In re Kahn, 441 F.3d 977, 986, 78 USPQ2d 1329, 1337 (Fed. Cir. 2006).                              
                        We are in agreement with Appellants that, in this case, a prima facie                           
                 showing of obviousness based on the applied prior art required, at a                                   
                 minimum, some explanation as to why one of ordinary skill in the art would                             
                 have selected polyquaternium 37 from Cotteret’s extensive list of cationic                             
                 polymers.  The Examiner has not directed us to any objective teaching in the                           
                 prior art or identified the information generally available to one of ordinary                         
                 skill in the art which would have led that individual to select polyquaternium                         
                 37, or any other cationic homopolyer having the claimed formula (I), for use                           
                 in Narasimhan’s composition.  See In re Fine, 837 F.2d 1071, 1075, 5 USPQ                              


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