Ex Parte Wolffe et al - Page 1




                   The opinion in support of the decision being entered today was not written                 
                           for publication and is not binding precedent of the Board.                         
                                                                                                             
                           UNITED STATES PATENT AND TRADEMARK OFFICE                                          
                                                 __________                                                   
                                BEFORE THE BOARD OF PATENT APPEALS                                            
                                           AND INTERFERENCES                                                  
                                                 __________                                                   
                               Ex parte   ALAN WOLFFE and FYODOR URNOV                                        
                                                 __________                                                   
                                            Appeal No. 2006-2851                                              
                                          Application No. 09/844,501                                          
                                                 __________                                                   
                                                 ON BRIEF                                                     
                                                 __________                                                   
            Before ADAMS, MILLS, and GRIMES, Administrative Patent Judges.                                    
            MILLS, Administrative Patent Judge.                                                               

                                           DECISION ON APPEAL                                                 
                   This is a decision on appeal under 35 U.S.C. § 134 from the examiner's final               
            rejection of claims 123-152.                                                                      
                   Claims 123 reads as follows:                                                               
                   123.  A method for preparing a library of regulatory DNA sequences from a cell,            
            the method comprising:                                                                            
                   (a) providing a cell nucleus, wherein the nucleus comprises cellular chromatin;            
                   (b) contacting the nucleus with a first enzyme, wherein the first enzyme reacts            
            with accessible regions of cellular chromatin;                                                    
                   (c) deproteinizing the cellular chromatin to generate deproteinized DNA;                   










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