Ex Parte Wolffe et al - Page 6




            Appeal No. 2006-2851                                                                              
            Application No. 09/844,501                                                                        


            35 U.S.C. § 103(a)                                                                                
                   Claims 129, 131-133 and 152 stand rejected under 35 U.S.C. § 103(a) over                   
            Grosveld taken with Li.  Claims 136-142 stand rejected under 35 U.S.C. § 103(a) over              
            Grosveld taken with NEB catalog (1995).  Claims 134 and 146 stand rejected under                  
            35 U.S.C. § 103(a) over Grosveld taken with Chung.                                                
                   With respect to the other pending obviousness rejections before us, all rejections         
            stand or fall on the relevance of Grosveld to the pending claims.   The examiner relies           
            on the NEB catalog to make up for a failure of Grosveld to teach specific restriction             
            enzymes (Answer, page 6), Li for a failure of Grosveld to teach a comparison of cells             
            from a variety of different sources (Answer, page 7), and Chung for the failure of                
            Grosveld to teach embedding cells in agarose prior to enzymatic cleavage (Answer,                 
            page 9).                                                                                          
                   We do not find that either NEB catalog, Li or Chung overcome the above noted               
            deficiency of Grosveld  and its failure to teach steps (e) and (f) of claim 123, and              
            therefore the rejections for obviousness over Grosveld taken with NEB catalog, Li or              
            Chung are reversed.                                                                               


                                               CONCLUSION                                                     
                   The rejections of the claims under 35 U.S.C. § 103(a) over Grosveld alone or in            
            view of NEB, Li or Chung are reversed.                                                            

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