Ex Parte SPAULDING - Page 2

                  Appeal 2006-3206                                                                                              
                  Application 09/550,276                                                                                        

                  United States patent number for Izumi in the Supplemental Answer mailed                                       
                  May 22, 2006 (Supplemental Answer 3 and 7).                                                                   
                          The record shows that Appellant submitted a substituted specification                                 
                  and abstract with the amendment filed August 12, 2002, making certain                                         
                  statements with respect to 37 C.F.R. § 1.125 (2002) at page 6.  The status of                                 
                  this document is not apparent on the record.  In the final action mailed                                      
                  November 12, 2002, the Examiner stated “[t]he Office acknowledges receipt                                     
                  of the substituted specification” at page 2, which statement does not indicate                                
                  whether the substitute specification complied with said rule and MPEP                                         
                  § 1211 (8th ed., August 2001) and has been entered in the record.  Indeed,                                    
                  the Examiner has not stated that the document is entered (no markings to                                      
                  that effect are on the document) and refers to the original specification with                                
                  respect to “Surmodics, Inc.” (Supplemental Answer 3 and 9).                                                   
                          We copy appealed independent claims 1 and 10 and representative                                       
                  dependent claims 11, 21, and 24 as they appear in the Claims Appendix to                                      
                  the Brief:                                                                                                    
                          1. A cytometer apparatus comprising:                                                                  
                          a rotating means adapted to receive and rotate a transparent cylinder                                 
                  along a longitudinal axis of the transparent cylinder;                                                        
                          a light source for illuminating at least a portion of said transparent                                
                  cylinder while the transparent cylinder is being rotated by the rotating                                      
                  means;                                                                                                        
                          a detector for detecting a light signal provided by said light source and                             
                  reflected from said transparent cylinder while the transparent cylinder is                                    
                  being rotated by the rotating means;                                                                          
                          determining means for determining at least one cytometric                                             
                  characteristic of a sample disposed in said transparent cylinder based  on                                    
                  said light signal; and                                                                                        

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