Appeal 2004-1103 Application 09/733,387 According to appellants (Request, page 2, emphasis removed), [g]iven the scientific evidence of record, there can be no question that those skilled in the art would clearly believe that [a]ppellants’ sequence is a functional protein, as opposed to the assertion by the [e]xaminer that “there is no sufficient and credible information that indicates the published sequence is truly function GPCR” . . . . In support of this assertion, appellants’ Request raises five points which appellants believe the Board failed to consider in reaching its Decision. Id. We will take each in turn. 1. Appellants assert (id., emphasis removed) that “[s]equences sharing between 90-100% percent identity at the protein level over the entire length of the claimed sequence are present in the leading scientific repository for biological sequence data (GenBank).” We note, however, that simply demonstrating that sequences sharing some degree of identify with appellants’ disclosed sequence are known in GenBank does nothing to establish a utility for the invention of claim 1. Accordingly, without more, we are not persuaded by this argument. 2. Apparently, recognizing that the GenBank sequence data alone is insufficient to establish a utility for the invention of claim 1, appellants direct attention to five post-filing date references (see Brief, Exhibits A-E). Request, page 2. According to appellants (id.), these references demonstrate that “third party scientists” annotated the GenBank sequences as G protein-coupled receptors. While we would agree that post-filing date references can be used as evidence of the level of ordinary skill in the art at the time of the application,2 appellants have not demonstrated that at the time of appellants’ claimed invention a person of ordinary skill in the art would have recognized that these GenBank sequences demonstrate that appellants’ claimed sequence is a functional G protein-coupled receptor. At best, appellants have demonstrated that after their filing date, sequences with some degree of similarity to their own 2 In re Hogan, 559 F.2d 595, 605, 194 USPQ 527, 537 (CCPA 1977) (“This court has approved use of later publications as evidence of the state of the art existing on the filing date of an application.” (footnote omitted)). 2Page: Previous 1 2 3 4 5 6 7 Next
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