Ex Parte Selzer - Page 3

                 Appeal No. 2006-0760                                                                                  
                 Application No. 10/312,417                                                                            

                        d) a contact adhesive layer for attachment of the dermal therapeutic                           
                        system to the skin and which is optionally identical to the layer                              
                        containing the medical substance; and                                                          
                        e) a protective layer.                                                                         
                                      Anticipation under 35 U.S.C. § 102(e)                                            
                        Claims 13-19 stand rejected under 35 U.S.C. § 102(e) as anticipated                            
                 by Levin.                                                                                             
                        Levin1 describes “cetyl myristoleate (CMO) and CMO compounds in                                
                 combination with other compounds useful for treating inflammatory                                     
                 disease.”  (Levin at 2, ll. 8-10.)  Cox-2 inhibitors are listed by Levin in a                         
                 group of others compounds which can be combined with CMO (id. at 3, ll.                               
                 27-33).  Levin states that “[c]ompositions of the invention can be                                    
                 administered by a variety methods which are well known in the art.  Routes                            
                 of administration include, but are not limited to oral, topical, sublingual,                          
                 rectal, intranasal, intraocular, intravenous, intramuscular, transdermal, and                         
                 by inhalation.”  (Id. at 11, ll. 14-17.)                                                              
                        The Examiner asserts that Levin teaches the limitations recited in                             
                 claim 13.                                                                                             
                        Levin teaches compositions comprising COX-2 inhibitors                                         
                        (NSAIDS) including celecoxib [its chemical name “4-[5-aryl-3-                                  
                        (trifluoromethylpyrazol-1-yl]benzenesulfonamides” is recited in                                
                        claim 13] and rofecoxib [its chemical name “3-aryl-4-(4-                                       
                        methylsulfonylphenyl)-2(H5) furanones” is recited in claim 13]                                 
                        formulated in transdermal bandages or patches for topical                                      
                        administration. (abstract, page 7, lines 7-9, page 11, lines 14-17,                            
                        page 12, lines 9-1, page 21, claim 42).                                                        
                 (Answer 4.)                                                                                           
                                                                                                                      
                 1 Levin, WO 01/41783 A1, published Jun. 14, 2001.                                                     

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