Ex Parte Selzer - Page 10

                 Appeal No. 2006-0760                                                                                  
                 Application No. 10/312,417                                                                            

                 transdermal administration suggests, contrary to Appellant’s argument, that                           
                 the person of ordinary skill in the art would have reasonably believed that                           
                 transdermal delivery was not limited by a compound’s structure.                                       
                 For the foregoing reasons, we affirm the rejection of claim 20 as                                     
                 obvious over Levin in view of Lee.  Because claims 21-27 were not                                     
                 separately argued, they fall with claim 20.                                                           
                                                  OTHER ISSUES                                                         
                        PCT International Publication WO 00/00120 was cited in an                                      
                 Information Disclosure Statement filed December 23, 2002.  It is in the same                          
                 patent family as the Murdock6 patent, having a filing date of at least Jun. 29,                       
                 1999, which is earlier than the filing date of the instant application.                               
                 Murdock discloses a transdermal composition which comprises a non-                                    
                 steroidal anti-inflammatory compound.  Celecoxib and Vioxx® are                                       
                 specifically mentioned (Col. 2, ll. 48-54; col. 8, ll. 44-47).  In Example 73,                        
                 celecoxib is formulated with solvents and carriers as a gel for transdermal                           
                 use (Col. 31, ll. 40-45).  The Examiner should consider whether this                                  
                 example (and/or other disclosure in Murdock) anticipates and/or makes                                 
                 obvious the subject matter of claim 13 (and other pending claims), alone, or                          
                 in combination with other prior art.                                                                  
                        We also draw the Examiner’s to U.S. Pat. 5,466,8237 which discloses                            
                 celecoxib, a compound of Formula I (Col. 4, ll. 64-65).  The patent discloses                         
                 that Formula I compounds can be administered topically (Col 47, l. 24).  The                          
                 Examiner should consider whether this disclosure anticipates and/or makes                             
                                                                                                                      
                 6 Murdock et al., U.S. Patent 6,479,074 B2, issued Nov. 12, 2002.                                     
                 7 Talley et al. U.S. Patent 5,466,823, issued Nov. 14, 1995.                                          

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