Ex Parte Ridgway - Page 6

                Appeal  2006-2372                                                                                  
                Application 10/854,708                                                                             
                1741, 82 USPQ2d 1385, 1396 (2007).  See also id. at 1742, 82 USPQ2d at                             
                1397 (“A person of ordinary skill is also a person of ordinary creativity, not                     
                an automaton.”).  In this regard, we note that “[w]hen a work is available in                      
                one field of endeavor, design incentives and other market forces can prompt                        
                variations of it, either in the same field or a different one.  If a person of                     
                ordinary skill can implement a predictable variation, § 103 likely bars its                        
                patentability.”  Id. at 1740, 82 USPQ2d at 1396.                                                   
                       In our opinion, a person of ordinary skill in the art at the time the                       
                invention was made would have readily understood that Jennings’ method                             
                could have been predictably improved by performing all of the method steps                         
                in a single tube.  We find no evidence on this record that this modification or                    
                variation in Jennings’ method would have been unpredictable or produced                            
                an unexpected result.  Instead, as the Examiner explains, a person of                              
                ordinary skill in the art would have realized that maintaining the sample in a                     
                single tube reduces the risk of contaminating not only the sample but those                        
                involved in performing the method (Answer 5 - 8).                                                  
                       Further, we are not persuaded by Appellant’s argument based on                              
                Jennings’ teaching that the use of two tubes provides an opportunity to                            
                perform “duplicate runs of a specimen if questionable results were initially                       
                obtained” (Jennings 15: 32-33).  We find that the Examiner has provided a                          
                plausible rationale as to why a person of ordinary skill in the art would                          
                perform the method in a single tube, specifically to limit the possibility of                      
                contamination of both the sample and personnel performing the method.  It                          
                is well settled that obviousness analyses involving potential modifications of                     
                the prior art entail weighing the relative trade-offs of the various                               
                alternatives.  See Medichem S.A. v. Rolabo S.L., 437 F.3d 1157, 1165, 77                           

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