Ex Parte Nash et al - Page 24

                 Appeal No. 2006-2575                                                                                  
                 Application No. 10/025,567                                                                            

                        Moreover, the Examiner has not shown that the cited references                                 
                 would have suggested to one of ordinary skill in the art seeking to produce                           
                 protective antibodies against P. anaerobius, C. sticklandii, and                                      
                 C. aminophilum that it would have been desirable to make compositions                                 
                 containing antibodies to the culture supernatants of those organisms, rather                          
                 than the cells.  Nor has the Examiner shown that one of ordinary skill would                          
                 have had a reasonable expectation that inoculating birds with the culture                             
                 supernatants of P. anaerobius, C. sticklandii, and C. aminophilum, rather                             
                 than whole cells, would have yielded antibodies capable of inhibiting the                             
                 organism in the digestive tracts of food animals.                                                     
                        Thus, in our view, the Examiner has not established that one of                                
                 ordinary skill would have been motivated to produce compositions                                      
                 containing antibodies to P antigen from P. anaerobius, CS antigen from                                
                 C. sticklandii, or CA antigen from C. aminophilum, with a reasonable                                  
                 expectation that inoculating birds with P, CS, or CA antigen would have                               
                 successfully produced antibody capable of inhibiting P. anaerobius,                                   
                 C. sticklandii, or C. aminophilum.  We therefore reverse the obviousness                              
                 rejection of claims 13, 16 and 19.                                                                    
                        To summarize, Tokoro describes a composition encompassed by                                    
                 representative claim 5.  We therefore affirm the obviousness rejection of                             
                 claims 1, 3 and 5.  However, because the cited references do not teach or                             
                 suggest preparing a dried avian egg composition containing antibodies to P,                           
                 CS, or CA antigens, we reverse the obviousness rejection of claims 13, 16,                            
                 and 19.                                                                                               



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