Appeal No. 2006-2575 Application No. 10/025,567 Moreover, the Examiner has not shown that the cited references would have suggested to one of ordinary skill in the art seeking to produce protective antibodies against P. anaerobius, C. sticklandii, and C. aminophilum that it would have been desirable to make compositions containing antibodies to the culture supernatants of those organisms, rather than the cells. Nor has the Examiner shown that one of ordinary skill would have had a reasonable expectation that inoculating birds with the culture supernatants of P. anaerobius, C. sticklandii, and C. aminophilum, rather than whole cells, would have yielded antibodies capable of inhibiting the organism in the digestive tracts of food animals. Thus, in our view, the Examiner has not established that one of ordinary skill would have been motivated to produce compositions containing antibodies to P antigen from P. anaerobius, CS antigen from C. sticklandii, or CA antigen from C. aminophilum, with a reasonable expectation that inoculating birds with P, CS, or CA antigen would have successfully produced antibody capable of inhibiting P. anaerobius, C. sticklandii, or C. aminophilum. We therefore reverse the obviousness rejection of claims 13, 16 and 19. To summarize, Tokoro describes a composition encompassed by representative claim 5. We therefore affirm the obviousness rejection of claims 1, 3 and 5. However, because the cited references do not teach or suggest preparing a dried avian egg composition containing antibodies to P, CS, or CA antigens, we reverse the obviousness rejection of claims 13, 16, and 19. 24Page: Previous 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Next
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