Ex Parte Irvin et al - Page 4

               Appeal 2006-2729                                                                            
               Application 10/193,363                                                                      

               thus explicitly sets forth the requirement that encompassed functional                      
               material and surfactants have the claimed relative properties, “i.e., the                   
               functional material is substantially insoluble in the compressed CO2 in the                 
               absence of the surfactant, and the surfactant comprises a compressed CO2-                   
               philic portion and a functional material-philic portion” (id.).                             
                      The Examiner responds “[i]t is unclear what combination of                           
               functional materials and surfactants form aggregates . . . and how one skilled              
               in the art would specifically selected said combination” (Answer 16).                       
               Appellants reply they addressed the Examiner’s enablement concerns with                     
               respect to that ground of rejection (Reply Br. 8).                                          
                      With respect to the rejection of independent claim 1 under § 112, first              
               paragraph, enablement requirement, the Examiner finds the Specification                     
               enabling for specific nanoparticulate materials exemplified therein, but does               
               not reasonably provide enablement for all functional material including                     
               guidance for generically specified functional materials such as the group of                
               such materials set forth in claim 10 (Answer 3-5).  The Examiner concludes                  
               “[t]he formation of particles having 0.5 to 10 nm particle size is material                 
               specific and appellants’ claimed breadth would require undo                                 
               experimentation for all materials broadly listed in the specification and claim             
               10 to form said nanoparticles” (id. 3 and 5-6).                                             
                      Appellants contend the Examiner has not carried the burden of                        
               establishing that the disclosure in the Specification does not enable the                   
               claims in compliance with § 112, first paragraph, enablement requirement                    
               (Br. 9).  Appellants contend the Specification provides general guidance and                
               specific examples which one skilled in the art with basic knowledge of the                  


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