Ex Parte Glover et al - Page 8

                Appeal No. 2006-2861                                                                          
                Application No. 10/007,272                                                                    

                have been expected to contain even a single crystal of Form II, Form V, or                    
                ethanol solvate of the known compound.  While the burden of proof can be                      
                shifted to an applicant in appropriate cases, the Office first must show a                    
                reasonable basis for concluding that the claims read on the prior art.  See In                
                re Wilder, 429 F.2d 447, 450, 166 USPQ 545, 548 (CCPA 1970) (“[I]n an ex                      
                parte proceeding to obtain a patent, . . . the Patent Office has the initial                  
                burden of coming forward with some sort of evidence tending to disprove                       
                novelty.”); In re Spada, 911 F.2d 705, 708, 15 USPQ2d 1655, 1658 (Fed.                        
                Cir. 1990) (“[W]hen the PTO shows sound basis for believing that the                          
                products of the applicant and the prior art are the same, the applicant has the               
                burden of showing that they are not” (emphasis added).).  No such basis has                   
                been shown on this record.                                                                    



















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