Ex Parte Eastman et al - Page 5

                Appeal 2006-3381                                                                               
                Application 10/162,317                                                                         
                          1. Appellants’ arguments center around the second limitation,                        
                             concerning the flexible membrane.  Brackett has two flexible                      
                             membranes, “thin flexible plastic film” (col. 2, l. 60) element                   
                             12, which is placed on the substrate 14 below the specimen 15,                    
                             and “relatively thin plastic film 18 that preferably is of the same               
                             thickness, material and size as film 12” (col. 3, ll. 8-10).  Film                
                             18 is placed above the specimen, and is used by the Examiner                      
                             to anticipate membrane 26 of the claimed invention.                               
                          2. We find that the film 18 of Brackett is placed “over at least a                   
                             substantial portion of said base member including said                            
                             window”.                                                                          
                          3. We find in Brackett the description, “[d]uring cover slipping,                    
                             film 18 preferably is aligned with one edge of film 12 … and                      
                             then wiped toward the opposite edge to squeeze out excess                         
                             mounting medium and prevent bubbles of air or fluid from                          
                             being trapped between the films 12, 18.  This will provide a                      
                             film-specimen-film sandwich” (col. 3, l. 10-15).  We note from                    
                             the drawings in Brackett that specimen 15, with liquid                            
                             mounting medium 17, is near the center of the window, with                        
                             liquid mounting medium “placed over the specimen and                              
                             adjacent areas” (col. 3, top, Fig. 5).  The Examiner has stated                   
                             that the claim language “in which said membrane is sufficiently                   
                             pliable in response to pressure to be capable of being operated                   
                             upon to reach said window at one or more locations to shape                       
                             the tissue specimen upon said window” is anticipated by this                      

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