Ex Parte Zhang et al - Page 5

             Appeal No. 2007-0179                                                          Page 5              
             Application No. 10/601,856                                                                        

                   agent), adjusts the pH of the composition. Thus, one would have been                        
                   motivated to utilize the desired acid: salt ratio depending on the                          
                   desired pH of the composition. For instance, Jokura teaches the                             
                   importance of avoiding skin irritation due to the acid; thus the pH                         
                   must be above 3 and below 10 (see column 3, lines 30-65). Therefore,                        
                   a skilled artisan would have been motivated to use a sufficient amount                      
                   of salt to either partially or fully neutralize the acid in the composition                 
                   to render a pH that does not irritant the skin wherein using equimolar                      
                   amounts of the salt and acid (full neutralization) would increase the                       
                   pH whereas partial neutralization of the acid would decrease the pH                         
                   since the compound is in an acidic form. Additionally, it should be                         
                   noted that generally differences in concentrations do not support the                       
                   patentability of subject matter that is encompassed by the prior art                        
                   unless there is evidence indicating such a[ ] concentration is critical.                    
                   See In re Aller, 220 F.2d 454, 456, 105 USPQ 233, 235 (CCPA 1955).                          
             Id. at 5: 6-20.                                                                                   
                   Appellants argue that Jokura “is focused upon achieving moisturization.                     
             There is no suggestion that the dicarboxylic acids implicated in achieving this                   
             moisturization would have any effectiveness at stabilizing sunscreen agents” as                   
             described in the instant application.  Br. 5.  They also assert that that half-                   
             neutralized and fully neutralized dicarboxylic acids are not described by Jokura.                 
             “Since the free acid must be present, the fully neutralized salt of that free acid                
             could not coexist therewith. . . .  Jokura et al. lacks the claimed di-salt.”  Br. 7.             
             Appellants urge there would have been no motivation to have selected malonic                      
             salts from Jokura’s disclosure.  Br. 6, 8.                                                        
                   The Examiner bears the initial burden of showing unpatentability.  See, e.g.,               
             In re Rijckaert, 9 F.3d 1531, 1532, 28 USPQ2d 1955, 1956 (Fed. Cir. 1993).                        
             Obviousness requires assessing “if the differences between the subject matter                     
             sought to be patented and the prior art are such that the subject matter as a whole               
             would have been obvious at the time the invention was made to a person having                     




Page:  Previous  1  2  3  4  5  6  7  8  9  10  11  Next

Last modified: September 9, 2013