Appeal No. 2007-0179 Page 5 Application No. 10/601,856 agent), adjusts the pH of the composition. Thus, one would have been motivated to utilize the desired acid: salt ratio depending on the desired pH of the composition. For instance, Jokura teaches the importance of avoiding skin irritation due to the acid; thus the pH must be above 3 and below 10 (see column 3, lines 30-65). Therefore, a skilled artisan would have been motivated to use a sufficient amount of salt to either partially or fully neutralize the acid in the composition to render a pH that does not irritant the skin wherein using equimolar amounts of the salt and acid (full neutralization) would increase the pH whereas partial neutralization of the acid would decrease the pH since the compound is in an acidic form. Additionally, it should be noted that generally differences in concentrations do not support the patentability of subject matter that is encompassed by the prior art unless there is evidence indicating such a[ ] concentration is critical. See In re Aller, 220 F.2d 454, 456, 105 USPQ 233, 235 (CCPA 1955). Id. at 5: 6-20. Appellants argue that Jokura “is focused upon achieving moisturization. There is no suggestion that the dicarboxylic acids implicated in achieving this moisturization would have any effectiveness at stabilizing sunscreen agents” as described in the instant application. Br. 5. They also assert that that half- neutralized and fully neutralized dicarboxylic acids are not described by Jokura. “Since the free acid must be present, the fully neutralized salt of that free acid could not coexist therewith. . . . Jokura et al. lacks the claimed di-salt.” Br. 7. Appellants urge there would have been no motivation to have selected malonic salts from Jokura’s disclosure. Br. 6, 8. The Examiner bears the initial burden of showing unpatentability. See, e.g., In re Rijckaert, 9 F.3d 1531, 1532, 28 USPQ2d 1955, 1956 (Fed. Cir. 1993). Obviousness requires assessing “if the differences between the subject matter sought to be patented and the prior art are such that the subject matter as a whole would have been obvious at the time the invention was made to a person havingPage: Previous 1 2 3 4 5 6 7 8 9 10 11 Next
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