Ex Parte Zhang et al - Page 6

             Appeal No. 2007-0179                                                          Page 6              
             Application No. 10/601,856                                                                        

             ordinary skill in the art to which said subject matter pertains.”  35 U.S.C. § 103(a).            
             To establish a prima facie case of obviousness, there must be some suggestion or                  
             motivation, either in the references themselves or in the knowledge generally                     
             available to one of ordinary skill in the art, to modify the reference or to combine              
             reference teachings.  See In re Vaeck, 947 F.2d 488, 20 USPQ2d 1438 (Fed. Cir.                    
             1991); In re Dembiczak, 175 F.3d 994, 999, 50 USPQ2d 1614, 1617 (Fed. Cir.                        
             1999).  “The prima facie case is a procedural tool of patent examination, allocating              
             the burdens of going forward as between examiner and applicant. . . .  If that                    
             burden is met, the burden of coming forward with evidence or argument shifts to                   
             the applicant.”  In re Oetiker, 977 F2d 1443, 1445, 24 USPQ2d 1443, 1444 (Fed.                    
             Cir. 1992).                                                                                       
                   Here, we find that the Examiner has presented sufficient evidence to                        
             establish a prima facie case of obviousness.  First, the Examiner has identified                  
             where the components of the claimed composition can be found in the prior art.                    
             Answer 3-4.  Secondly, having described the differences between the claimed                       
             composition and the prior art (Answer 4), the Examiner explains why the skilled                   
             worker would have been motivated to have modified Jakura to have arrived at the                   
             claimed subject matter.  Answer 4-5.                                                              
                   Before summarizing the Examiner’s position, for clarity, we designate the                   
             free dicarboxylic acid (i.e., malonic acid) as species [1]; the half- or partly-                  
             neutralized acid (i.e., malonic acid substituted with one “cationic counter ion”) as              
             species [2]; and the fully-neutralized acid (i.e., malonic acid substituted with two              
             “cationic counter ions”; the “di-salt”) as species [3].  Jokura describes a skin                  
             composition having a molar ratio between the free acid [1] and fully neutralized                  
             acid [3].  Col. 3, ll. 51-60.  In contrast, the claimed composition is limited to a               
             different molar ratio which is between the half-neutralized [2] and fully neutralized             



Page:  Previous  1  2  3  4  5  6  7  8  9  10  11  Next

Last modified: September 9, 2013