Ex Parte Faryniarz et al - Page 5

                Appeal 2007-0535                                                                                 
                Application 10/601,731                                                                           

                composition and the instant composition . . . will exhibit the same property,                    
                i.e. the instant flexibility value.”  (Id.)                                                      
                       We agree that the Examiner has set forth a prima facie case that the                      
                composition of claim 1 would have been obvious.  Jokura describes a skin                         
                cosmetic comprising a ceramide or pseudoceramide, a dicarboxylic acid, and                       
                a salt of a dicarboxylic acid (Jokura, col. 2, ll. 6-39), and specifically                       
                identifies malonic acid as an example of a dicarboxylic acid (id. at col. 3,                     
                ll. 33-37).  Jokura states that preferably “the total content of [the                            
                dicarboxylic acid] and [dicarboxylic acid salt], in terms of the acid, in the                    
                skin cosmetic . . . falls within a range of from 0.01 to 20% by weight” and                      
                “the molar ratio of the [dicarboxylic acid] to [dicarboxylic acid salt] falls                    
                within a range of from 1/9 to 9/1” (id. at col. 3, ll. 51-60).  Jokura also                      
                describes including water, ethanol, or water-soluble polyhydric alcohols as a                    
                base and that the preferred content of these components in the skin cosmetic                     
                “ranges from 0.01 to 95% by weight” (id. at col. 4, ll. 16-34).                                  
                       As discussed above, the Specification states that malonate salts                          
                “impart to the composition a positive Flexibility Value of at least 1,                           
                preferably at least 1.1 relative to water in the Porcine Skin Test”                              
                (Specification 5).  Thus, we agree that the Examiner has set forth a prima                       
                facie case that the compositions of Jokura that contain malonic acid salt as                     
                the dicarboxylic acid salt would exhibit a Flexibility Value greater than 1.                     
                       Jokura does not state that malonic acid is present as a half neutralized                  
                acid and as a fully neutralized acid in a molar ratio ranging from about                         
                1000:1 to about 1:1000, respectively.  However, Jokura describes regulating                      



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