Ex Parte Faryniarz et al - Page 13

                Appeal 2007-0535                                                                                 
                Application 10/601,731                                                                           

                (from about 3 to about 99.85% by weight) and “is adjusted to a pH of from                        
                about 3.0 to about 6.0” (id.).  Beerse states that the composition is “suitable                  
                for application to the human skin for the purpose of removing dirt, oil and                      
                the like” and “can also be useful for treatment of acne” and “for providing                      
                an essentially immediate (i.e., acute) visual improvement in skin appearance                     
                following application of the composition to the skin,” including regulating                      
                “discontinuities associated with skin aging” (id. at 4-5).                                       
                       Beers defines a “proton donating agent” as “any acid compound or                          
                mixture thereof, which results in undissociated acid on the skin after use”                      
                (id. at 18).  As a proton donating agent, Beerse describes organic acids, such                   
                as malonic acid (id. at 19).  In Example 14, Beerse describes a composition                      
                comprising 4% malonic acid and 3.2% sodium malonate in water (id. at 36).                        
                We agree that the Examiner has set forth a prima facie case that the broad                       
                molar ratio recited in claim 1 would have been obvious based on the                              
                teachings of Beerse and that the compositions of Beerse that contain malonic                     
                acid as the proton donating agent would exhibit a Flexibility Value greater                      
                than 1 for substantially the same reasons as with Jokura.                                        
                       Appellants argue that “Beerse does not disclose a half neutralized salt                   
                of malonic acid.  There is reference to only one malonate salt mentioned.  It                    
                is not known whether the ‘sodium malonate’ is meant to be disodium                               
                malonate (fully neutralized) or sodium hydrogen malonate (half neutralized)                      
                variant.”  (Br. 11.)                                                                             
                       We are not persuaded by this argument.  For the reasons discussed                         
                above (supra, at pp. 6-7), whether “sodium malonate” refers to the fully                         
                neutralized salt or the half neutralized salt, once this component is added to                   


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