Ex Parte Keller et al - Page 7

               Appeal 2007-0650                                                                            
               Application 10/808,264                                                                      
                      We cannot say that Appellants have provided sufficient                               
               evidence and/or reasoning to support a determination that those of                          
               ordinary skill in the art would not have been able to synthesize the                        
               x = 7, 8, 9, or 10 aromatic diols of Keller.  Looking at the issue                          
               through the facts of the cases that have construed “possession” in the                      
               context of what is enabling, we note that prior art references were                         
               found to be non-enabled when there was a complete absence of a                              
               known or obvious method of making the product in a stable form.  See                        
               In re Brown, 329 F.2d 1006, 1011, 141 USPQ 245, 249 (CCPA 1964)                             
               (“[W]e do not think that Clark's reference to his unsuccessful attempts                     
               to prepare fluorine-containing silicone homopolymers would place                            
               such homopolymers in the possession of the public” (emphasis                                
               added)); In re Sheppard, 339 F.2d 238, 241-42, 144 USPQ 42, 45                              
               (CCPA 1964) (“Emelus indicates a complete lack of success in                                
               preparation of pentafluorides” in a stable form (emphasis added)); In                       
               re Hoeksema, 399 F.2d 269, 274, 158 USPQ 596, 601 (CCPA 1968)                               
               (“[T]he absence of a known or obvious process for making the                                
               claimed compounds overcomes a presumption that the compounds are                            
               obvious.” (emphasis added)); In re Collins, 462 F.2d 538, 542-43, 174                       
               USPQ 333, 337 (CCPA 1972) (“[T]he lack of a teaching in Collins of                          
               how to make the presently claimed heat exchangers vitiates the                              
               rejection unless there was some known or obvious way to make                                
               them.” (emphasis added)).                                                                   
                      Appellants present no convincing evidence that those of                              
               ordinary skill in the art at the time of the invention would be unable to                   
               make the diols at issue.  Keller states that the aromatic diols “are                        

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