Ex Parte Bottcher et al - Page 8

                Appeal 2007-0736                                                                                
                Application 10/480,239                                                                          
                       16.  The skilled artisan would have been aware of and able to obtain                     
                the types of amorphous silicon dioxide support materials used by Appellants.                    
                (See Spec. 4, ll. 33-35 (“Suitable amorphous support materials based on                         
                silicon dioxide are well known to those skilled in the art and are                              
                commercially available.”).)                                                                     
                       17.  The skilled artisan would have been motivated to make the                           
                claimed ruthenium catalyst by using a commercially available amorphous                          
                silicon dioxide (based on the teachings of Shokal or Setoyama) as a support                     
                for ruthenium (based on the teachings in each of the references).  (FFs 6-16.)                  
                       18.  Further, the skilled artisan would have reasonably expected to                      
                succeed in preparing cycloaliphatic compounds such as Appellants’                               
                Compound I by hydrogenating compounds such as Appellants’ Compound                              
                II, based on the teachings of the three cited references.  (FFs 6-17.)                          
                       19.  Appellants have not provided any evidence of an unobvious                           
                difference between their ruthenium catalyst on an amorphous silicon dioxide                     
                support and those in the prior art, i.e., those of Shokal and Setoyama.                         
                Appellants’ “Unexpected Results”                                                                
                       20.  Appellants’ produced catalysts A and B (according to the                            
                invention) from ruthenium (III) nitrosyl nitrate and silica gel, reducing the                   
                ruthenium compound to ruthenium metal.  (Spec. 12-13.)                                          
                       21.  Appellants produced their comparative catalyst, hydrated                            
                ruthenium oxide, by reacting ruthenium (III) chloride hydrate with aqueous                      
                sodium hydroxide and then washing the product with water and THF.                               
                (Spec. 13 (similar to Schuster’s Example but failing to use Schuster’s closest                  
                teachings, i.e., ruthenium on an inert support (carbon)).)                                      



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