Ex Parte Krulevitch et al - Page 4



               Appeal 2007-1019                                                                       
               Application 09/851,231                                                                 

               “[e]ven if the microchannel half cavities 20 and 22 in Cammack et al. are              
               etched and subsequently annealed, and not formed by annealing as disclosed             
               in Appellants’ present invention, the end product is the same in structure as          
               that disclosed in Appellants’ present invention,” and Appellants have not              
               proffered evidence to the contrary (Answer 6, second para.).                           
                    As for product-by-process claims 17-19, it is well settled that when              
               prior art discloses a product which reasonably appears to be either identical          
               with or only slightly different than a product claimed in a product-by-                
               process claim, the burden is on the applicant to establish with objective              
               evidence that the products are not, in fact, substantially the same.  In re            
               Brown, 459 F.2d 531, 535, 173 USPQ 685, 688 (CCPA 1972).  In the                       
               present case, Appellants have not shouldered their burden of demonstrating             
               that their microchannels formed by annealing are substantially different than          
               the microchannels formed by etching in the Cammack patent.                             
                    As for the § 103 rejection of claims 12, 16, and 18, Appellants have              
               not rebutted the reasonable position articulated by the Examiner in the                
               Answer, but have only relied upon the asserted differences between                     
               microchannels formed by annealing and etching.  Appellants’ statement at               
               page 18 of the Brief that the differences between Cammack and Appellants’              
               invention defined by claims 12, 16, and 18 “includes the fact that the                 
               elements of claims 12, 16 and 18 are not found in the Cammack et al.                   
               reference” is not a substantive argument which sets forth why the differences          
               would have been nonobviousness to one of ordinary skill in the art within              

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