Appeal 2007-1040 Application 09/960,708 INTRODUCTION The claims are directed toward methods of inhibiting (a) angiogenesis/vascular development in a host (claims 8 and 46) or (b) tumor growth in a host (claims 15 and 47). The methods of claims 8 and 15 comprise the single step of systemically administering an effective amount of a Ca2+/calcineurin/NF-ATc inhibitory agent to the host. The methods of claims 46 and 47 comprise the single step of administering an effective amount of a cyclosporin to the host. Claims 8, 15, 46, and 47 are reproduced below: 8. A method of inhibiting angiogenesis/vascular development in a host having a condition associated with unwanted angiogenesis, said method comprising: systemically administering to said host an effective amount of a Ca2+/calcineurin/NF-ATc inhibitory agent to inhibit angiogenesis/vascular development in said host having a condition associated with unwanted angiogenesis. 15. A method of inhibiting tumor growth in a host having a neoplastic disease condition, said method comprising: systemically administering to said host having a neoplastic disease condition an effective amount of a Ca2+/calcineurin/NF-ATc inhibitory agent to inhibit tumor growth in said host. 46. A method of inhibiting angiogenesis/vascular development in a host having a condition associated with unwanted angiogenesis, said method comprising: administering to said host an effective amount of a cyclosporin to inhibit angiogenesis/vascular development in a host having a condition associated with unwanted angiogenesis. 2Page: Previous 1 2 3 4 5 6 7 8 9 10 11 Next
Last modified: September 9, 2013