Ex Parte Maes et al - Page 8

                Appeal 2007-1144                                                                             
                Application 10/424,616                                                                       

                instant Specification to decrease skin flakiness (Spec. 9-10).  If emollients                
                and humectants were known to decrease skin flaking, their addition to a self-                
                tanning composition may well have been expected to result in a longer-                       
                lasting tan, in which case the results of the Specification’s examples may                   
                have been entirely expected.  We find it significant in this regard that the                 
                Specification does not characterize as unexpected the more long-lasting tan                  
                that results from a composition containing cholesterol sulfate.                              
                      Therefore, we do not agree that Appellants have presented data                         
                demonstrating an unexpected result compared to the closest prior art, as                     
                required to rebut the Examiner’s prima facie case of obviousness.  We affirm                 
                the Examiner’s rejection of claims 13-16 over Miklean in view of Bernstein.                  
                4.  OBVIOUSNESS -- CERNASOV, MIKLEAN, AND BERNSTEIN                                          
                      Claims 15 and 16 stand rejected under 35 U.S.C. § 103 as obvious in                    
                view of Cernasov, Miklean and Bernstein (Answer 6).                                          
                      The Examiner reasons that it would have been obvious to include                        
                DHA and imidazole in a self-tanning composition because Miklean discloses                    
                that “a combination of imidazole and dihydroxyacetone provides a                             
                significantly darker skin than dihydroxyacetone alone” (id.).  Appellants                    
                argue that the references are not properly combined because Cernasov’s                       
                pigments produce a tan by a mechanism different than Miklean’s DHA and                       
                imidazole, and that nothing in Cernasov resolves the shortcomings of the                     
                combination of Miklean and Bernstein (Br. 11-12; Reply Br. 6-7).                             
                      We are not persuaded by these arguments.  As discussed above, one of                   
                ordinary skill would have recognized from Miklean and Bernstein that                         
                cholesterol sulfate would be a useful moisturizing ingredient in an artificial               


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