Appeal 2007-1148
Application 10/078,592
Beasley et al., Isolated human zinc protease proteins, nucleic acid molecules
encoding human protease proteins, and uses thereof. 08-OCT-2002 Issued
Patents DataBase SEQ ID NO:2. Alignment with SEQ ID NO:2.
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3. UTILITY
Claims 1 and 3-8 stand rejected under 35 U.S.C. §§ 101 and 112, first
paragraph, on the basis that the specification does not disclose a patentable
utility for the claimed nucleic acids. The Examiner reasons that
[p]roteases comprise a highly diverse group of enzymes, which
cleave a wide variety of different substrates at a wide variety of
motifs. The specification fails to identify specific substrates for
the protease encoded by the recited polynucleotides or specific
diseases to be treated with said putative protease. . . . As
proteases are such a large and diverse family of enzymes, a
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