Ex Parte Belanoff - Page 8

                Appeal  2007-1155                                                                                
                Application 10/230,575                                                                           
                for the deficiency in Schatzber ‘596.  Accordingly, we reverse the rejection                     
                of claims 1-15 under 35 U.S.C § 103(a) as unpatentable over the                                  
                combination of Schatzber ‘596 and Sekijima.                                                      

                OBVIOUSNESS-TYPE DOUBLE PATENTING:                                                               
                       Claims 1-15 stand rejected under the judicially created doctrine of                       
                obviousness-type double patenting as being unpatentable over claims 1-13 of                      
                Schatzberg ‘802.  The claims in Schatzberg ‘802 are directed to a method of                      
                treating mild cognitive impairment.  In the Examiner’s opinion, since the                        
                same active agent is administered the method of Schatzberg ‘802 and                              
                Appellants’ claimed methods overlap.  We disagree.  As discussed above,                          
                mild cognitive impairment and cognitive deterioration in Down’s syndrome                         
                are distinct impairments.  For the reasons set forth above, we find no                           
                evidence on this record to suggest that a method of treating mild cognitive                      
                impairment would be effective to inhibit cognitive deterioration in an adult                     
                patient with Down’s syndrome but without dementia.  Accordingly, we                              
                reverse the rejection of claims 1-15 under the judicially created doctrine of                    
                obviousness-type double patenting as being unpatentable over claims 1-13 of                      
                Schatzberg ‘802.                                                                                 

                       Claims 1-15 stand rejected under the judicially created doctrine of                       
                obviousness-type double patenting as being unpatentable over claims 1-20 of                      
                Schatzberg ‘046.  The Examiner finds that Schatzberg ‘046 is “drawn to a                         
                method of inhibiting progression toward dementia in a patient therein                            
                administering the same glucocorticoid receptor antagonist as the instantly                       
                claimed” (Answer 7-8).  According to the Examiner, the patient population                        

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