Ex Parte Krulevitch et al - Page 3

                Appeal 2007-1369                                                                                   
                Application 10/032,257                                                                             
                and is directly connected to the specimen treatment and analysis chamber                           
                and is constructed to receive tissue therefrom.                                                    
                       Appealed claims 1-5 and 16-19 stand rejected under 35 U.S.C.                                
                § 103(a) as being unpatentable over Krulevitch '217 or Krulevitch '474 in                          
                view of Pourahmadi.                                                                                
                       Appellants fail to set forth an argument that is reasonably specific to                     
                any particular claim on appeal.  Accordingly, all the appealed claims stand                        
                or fall together with claim 1.                                                                     
                       We have thoroughly reviewed each of Appellants' arguments for                               
                patentability.  However, we find ourselves in complete agreement with the                          
                Examiner's reasoned analysis and application of the prior art, as well as his                      
                cogent and thorough disposition of the arguments raised by Appellants.                             
                Accordingly, we will adopt the Examiner's reasoning as our own in                                  
                sustaining the rejection of record, and we add the following for emphasis                          
                only.                                                                                              
                       Appellants do not dispute the Examiner's factual determination that                         
                the Krulevitch patents disclose an instrument for biopsy and analysis of                           
                tissue comprising all the claimed features with the exception of a PCR                             
                reaction chamber having a heating unit adjacent to the PCR reaction                                
                chamber.  However, for the reasons set forth by the Examiner, we are                               
                convinced that it would have been obvious for one of ordinary skill in the art                     
                to modify the instrument of Krulevitch to include the claimed PCR reaction                         
                chamber in view of the Pourahmadi disclosure.  The Examiner properly                               
                points out that Krulevitch discloses that the instrument can be incorporated                       
                into a microfluid system comprising existing micro valves and pumps and is                         
                intended to be used for acquiring specimens for DNA analysis.  Pourahmadi,                         

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