Ex Parte Crandall - Page 8

                Appeal 2007-1412                                                                             
                Application 09/822,152                                                                       


                      the origin of the subject matter sought to be patented.  As                            
                      indicia of obviousness or nonobviousness, these inquiries may                          
                      have relevancy.                                                                        
                Where the claimed subject matter involves more than the simple substitution                  
                of one known element for another or the mere application of a known                          
                technique to a piece of prior art ready for the improvement, a holding of                    
                obviousness must be based on “an apparent reason to combine the known                        
                elements in the fashion claimed.”  KSR Int’l v. Teleflex, Inc., 127 S. Ct.                   
                1727, 1740-41, 82 USPQ2d 1385, 1396 (2007).  That is, “there must be                         
                some articulated reasoning with some rational underpinning to support the                    
                legal conclusion of obviousness.”  Id., 127 S. Ct. at 1741, 82 USPQ2d at                     
                1396 (quoting In re Kahn, 441 F.3d 977, 987, 78 USPQ2d 1329, 1336 (Fed.                      
                Cir. 2006)).  Such reasoning can be based on interrelated teachings of                       
                multiple patents, the effects of demands known to the design community or                    
                present in the marketplace, and the background knowledge possessed by a                      
                person having ordinary skill in the art.  KSR, 127 S. Ct. at 1740-41, 82                     
                USPQ2d at 1396.                                                                              

                      2. OBVIOUSNESS (Teaching away/Expectation of success)                                  
                      The determination of obviousness must consider, inter alia, whether a                  
                person of ordinary skill in the art would have been motivated to combine the                 
                prior art to achieve the claimed invention and whether there would have                      
                been a reasonable expectation of success in doing so. Brown & Williamson                     
                Tobacco Corp. v. Philip Morris, Inc., 229 F.3d 1120, 1124 [56 USPQ2d                         
                1456,1458-59] (Fed. Cir. 2000). Medichem S.A. v. Rolabo S.L., 437 F.3d                       


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