Ex Parte Fleischner - Page 8

                  Appeal 2007-1615                                                                                         
                  Application 10/693,442                                                                                   

                  been obvious to optimize the dosing interval based on empirical observation.                             
                  Indeed, Habeck indicates that “the next step will be to take a look at dosing                            
                  intervals” (id.).                                                                                        
                         The question of obviousness is resolved on the basis of underlying                                
                  factual determinations including: (1) the scope and content of the prior art;                            
                  (2) the level of ordinary skill in the art; (3) the differences between the                              
                  claimed invention and the prior art; and (4) secondary considerations of                                 
                  nonobviousness, if any.  Graham v. John Deere Co., 383 U.S. 1, 17 (1966).                                
                  The Supreme Court has recently emphasized that “the [obviousness] analysis                               
                  need not seek out precise teachings directed to the specific subject matter of                           
                  the challenged claim, for a court can take account of the inferences and                                 
                  creative steps that a person of ordinary skill in the art would employ.” KSR                             
                  Int’l v. Teleflex Inc., 127 S. Ct. 1727, 1741 (2007).  “Often, it will be                                
                  necessary for a court to look to interrelated teachings of multiple patents; the                         
                  effects of demands known to the design community or present in the                                       
                  marketplace; and the background knowledge possessed by a person having                                   
                  ordinary skill in the art, all in order to determine whether there was an                                
                  apparent reason to combine the known elements in the fashion claimed” (id.                               
                  at 1740-41).                                                                                             
                         We find that the Examiner has established that the combined                                       
                  teachings of the cited references, all of which pertain to the appetite                                  
                  suppressive effects of the Hoodia gordonii plant, and at least some of which                             
                  correlate that appetite suppressive effect with weight loss, would have                                  
                  provided a reason for one of ordinary skill in the art to administer Hoodia                              



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