Ex Parte Fleischner - Page 9

                  Appeal 2007-1615                                                                                         
                  Application 10/693,442                                                                                   

                  for an extended period of time, and to adjust the dosage to prevent the                                  
                  appetite from rebounding for the duration of the treatment period.                                       
                         We have carefully considered all of Appellant’s arguments, but are                                
                  not persuaded otherwise.                                                                                 
                         In particular, Appellant argues that the Examiner equates appetite                                
                  suppression and weight control, but “one of skill in the art would recognize                             
                  that the two concepts are not coterminus” (Appeal Br. 12).  Relying on the                               
                  Declaration of Albert M. Fleischner (dated December 21, 2005, hereinafter                                
                  “Decl. I”), Appellant argues that “[i]t is possible to cause weight loss                                 
                  without suppressing appetite” and “it is possible to suppress appetite without                           
                  causing weight loss” (Appeal Br. 13), thus, “appetite suppression may have                               
                  no effect on body weight” (id. at 14).  We do not disagree, but the distinction                          
                  is of no consequence in the present case because, as discussed above, the                                
                  references cited by the Examiner teach that the appetite suppressive effect of                           
                  Hoodia can indeed facilitate weight loss.                                                                
                         In a similar vein, Appellant argues that “[a]ppetite suppression . . .                            
                  may cause weight gain” (Appeal Br. 14).  Appellant cites Blundell3 for the                               
                  proposition that food, “the most widely-used appetite suppressant in the                                 
                  world can also cause weight gain” (id.).  We are not persuaded.  Again, the                              
                  references cited by the Examiner establish that Hoodia can suppress appetite                             
                  while reducing food intake, i.e., calorie intake, at the same time, and can                              
                  facilitate weight loss.                                                                                  


                                                                                                                          
                  3 Blundell, “Pharmacological Approaches to Appetite Suppression,” 2                                      
                  Trends in Pharmacol. Sci. 147157 (1991).                                                                 
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