Ex Parte Frederickson - Page 5

                 Appeal 2007-0861                                                                                      
                 Application 09/381,484                                                                                

                        [t]here is increasing evidence that the premature infant may                                   
                        require a dietary source of preformed 20 and 22 carbon long                                    
                        chain polyunsaturated fatty acids (LCPUFA).  These LCPUFA,                                     
                        especially arachidonic acid (AA, 20 : 4 n-6) and                                               
                        docosahexaenoic  acid  (DHA,  22:6  n-3),  are  necessary  for                                 
                        proper growth and development and are consistently found in                                    
                        human milk.                                                                                    
                 (Crozier, p. S96: Summary.)                                                                           
                        Schweikhardt teaches that the “newborn baby, particularly the                                  
                 premature baby, is . . . dependent on the exogenous supply of highly                                  
                 unsaturated polyethenoid fatty acids such as e.g. arachidonic and                                     
                 docosahexaenoic acids” (Schweikhardt, p. 1, ¶ 3).4  Schweikhardt discloses                            
                 a “fat mixture for infant feeds” containing ARA and DHA “in a ratio of                                
                 docosahexaenoic to arachidonic acid of 1:2.0 to 1:3.0, wherein the content of                         
                 arachidonic acid in the fat mixture is 0.12 to 1.0 wt.% and that of                                   
                 docosahexaenoic acid 0.05 to 0.5 wt %” (id. at p. 2, ¶ 4).                                            
                        The Examiner has calculated that the wt.% ranges recited in                                    
                 Schweikhardt correspond to 5-42 mg/100 kcal of ARA and 1.7-17 mg/100                                  
                 kcal of DHA, while Appellants have calculated the ranges to correspond to                             
                 6.3-52.9 mg/100 kcal ARA and 2.6-26.5 mg/100 kcal DHA.  The Examiner                                  
                 and Appellants therefore agree that Schweikhardt discloses ranges of ARA                              
                 and DHA that overlap those recited in claim 1.  Schweikhardt teaches that                             
                 the disclosed “fat mixture . . . is suitable for the preparation of infant and                        
                 premature baby feed” (id. at p. 5, ¶ 1).                                                              
                        We agree with the Examiner that those of ordinary skill in the art                             
                 would have considered it obvious, in view of the cited references, to                                 
                                                                                                                      
                 4 Our citations to Schweikhardt refer to the English-language translation.                            

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