Ex Parte KRIEGER - Page 14

                Appeal  2007-4148                                                                              
                Application 09/148,012                                                                         

                      If this application is subject to further prosecution, the Examiner                      
                should consider whether compounds having diametrically opposed                                 
                mechanisms – both increasing and decreasing SR-BI expression, or both                          
                increasing and decreasing SR-BI binding to lipoprotein – can all have the                      
                same overall effect of inhibiting uptake, binding or transport of cholesteryl                  
                ester by SR-BI., as required by claim 1.                                                       
                C.  Claim 16                                                                                   
                      Claim 16 depends on claim 11, which has been cancelled.  If this                         
                application is subject to further prosecution, the dependency of claim 16                      
                should be corrected.                                                                           
                                                 SUMMARY                                                       
                      We affirm the rejection of claims 1-9, 12, 15, 16, and 20-22 for lack                    
                of adequate written description and the rejection of claims 1-9, 15, 16, and                   
                20-22 for lack of enablement.                                                                  

                      No time period for taking any subsequent action in connection with                       
                this appeal may be extended under 37 C.F.R. § 1.136(a).                                        

                                                 AFFIRMED                                                      
                Ssc                                                                                            


                PATREA L. PABST                                                                                
                PABST PATENT GROUP LLP                                                                         
                400 COLONY SQUARE, SUITE 1200                                                                  
                1201 PEACHTREE STREET                                                                          
                ATLANTA, GA 30361                                                                              

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