Ex Parte Abo et al - Page 5

                Appeal 2007-4214                                                                             
                Application 10/330,372                                                                       
                disagreement appears to be how the language “by the total number of                          
                residues in the sequence over which the Chp polypeptide is compared,” i.e.,                  
                the denominator of the equation by which sequence identity is determined.                    
                According to the Examiner, that number is always 236 amino acids (see,                       
                e.g., Answer 7), and according to Appellants that number is the number of                    
                residues of the overlap region (see, e.g., Br. 19-20).  Appellants present                   
                FASTA comparisons2 comparing SEQ ID NOs:2, 6, 7, 8, 9, 12, and 13 to                         
                SEQ ID NO:2, in which 100% sequence identity is obtained over the overlap                    
                region.                                                                                      
                      We think Appellants have the better argument.  The FASTA                               
                comparisons submitted by Appellants demonstrate that it is not repugnant in                  
                the art to determine sequence identity based on the number of residues in the                
                overlap region.  In addition, as noted above, the Specification defines the                  
                denominator as “the total number of residues in the sequence over which the                  
                Chp polypeptide is compared.”  The Examiner’s interpretation reads out the                   
                portion “over which the Chp polypeptide is compared.”                                        
                      The Examiner appears to be concerned with the breadth of the claims                    
                if Appellants’ definition were accepted.  However, “breadth is not to be                     
                equated with indefiniteness.”  In re Miller, 441 F.2d 689, 693, 169 USPQ                     
                597, 600 (CCPA 1971); see also In re Hyatt, 708 F.2d 712, 714-15, 218                        
                USPQ 195, 197 (Fed. Cir. 1983).                                                              



                                                                                                            
                2 The FASTA comparisons were presented to the Examiner in a                                  
                Supplemental Paper submitted on August 8, 2006, date stamped December                        
                21, 2006.                                                                                    
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