Ex Parte Rosengart et al - Page 2


                 Appeal No.  2007-0531                                                          Page 2                   
                 Application No.  10/341,679                                                                             
                        The references relied upon by the examiner are:                                                  
                 Tischer et al. (Tischer)   5,219,739  Jun. 15, 1993                                                     
                 Hammond et al. (Hammond)  5,792,453  Aug. 11, 1998                                                      
                 Kovesdi et al. (Kovesdi)   5,851,806  Dec. 22, 1998                                                     
                 Ullrich et al. (Ullrich)    5,851,999  Dec. 22, 1998                                                    
                 Isner      6,121,246  Sep. 19, 2000                                                                     
                 Wolff et al. (Wolff)    6,228,844  May 8, 2001                                                          
                 French et al. (French), “Direct in vivo gene transfer into porcine myocardium                           
                 using replication-deficient adenoviral vectors,” Circulation, Vol. 90, No. 5, pp.                       
                 2414-2424 (1994)                                                                                        

                                             GROUNDS OF REJECTION                                                        
                        Claims 1-4, 6, 7, 10, 12 and 18 stand rejected under 35 U.S.C. § 103 as                          
                 being unpatentable over the combination of Hammond and Tischer.                                         
                        Claims 1, 3, 6, 10, 19 and 22 stand rejected under 35 U.S.C. § 103 as                            
                 being unpatentable over the combination of Isner and Tischer.                                           
                        Claims 1 and 12-18 stand rejected under 35 U.S.C. § 103 as being                                 
                 unpatentable over the combination of Isner, Tischer and Kovesdi.                                        
                        Claims 1 and 19-21 stand rejected under 35 U.S.C. § 103 as being                                 
                 unpatentable over the combination of Isner, Tischer, Wolff and French.                                  
                        Claims 1 and 22-23 stand rejected under 35 U.S.C. § 103 as being                                 
                 unpatentable over the combination of Isner, Tischer and Ullrich.                                        
                        We reverse the rejection under 35 U.S.C. § 103 over the combination of                           
                 Hammond and Tischer.  We vacate all remaining rejections in favor of new                                
                 grounds of rejection.                                                                                   









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