Ex parte KISHORE et al. - Page 17




                    Appeal No. 93-2460                                                                                                                                    
                    Application No. 07/590,647                                                                                                                            


                    specification disclosure would have enabled one skilled in the                                                                                        
                    art to make transgenic maize.  We need not make this                                                                                                  
                    determination, however, because we do not find the single,                                                                                            
                    disclosed example of maize protoplasts which express the variant                                                                                      
                    EPSPS sufficient to enable the one skilled in the art to make the                                                                                     
                    invention as broadly claimed.  That is, the method of claim 46                                                                                        
                    encompasses all monocot plant species.   However, Potrykus                                                                                            
                    discloses that in 1990, the filing date of the present                                                                                                
                    application, standard direct gene transfer procedures, were not                                                                                       
                    generally applicable to all monocots, but had only been                                                                                               
                    successful with maize and rice.  Thus, on these facts, we find                                                                                        
                    that successful results obtained for the regeneration of                                                                                              
                    transformed maize protoplasts do not enable those skilled in the                                                                                      
                    art to practice the full scope of the invention, absent undue                                                                                         
                    experimentation.  In re Goodman, 11 F.3d 1046, 1050, 29 USPQ2d                                                                                        
                    2010, 2013 (Fed. Cir. 1993), citing In re Wands, 858 F.2d at 737,                                                                                     
                    8 USPQ2d at 1404.                                                                                                                                     
                              As to the list of reference titles submitted by the                                                                                         
                    appellants, we are unable to discern on the basis of this                                                                                             
                    information alone, what was known in the art with respect to the                                                                                      
                    production of transgenic cereals at the time the application was                                                                                      
                    filed.  Absent the references themselves, it is not possible to                                                                                       

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