Ex parte ARCHIBALD et al. - Page 7




          Appeal No. 95-3340                                                           
          Application  07/939,172                                                      
          None of these structurally similar types are involved here.                  
          Moreover, generalization should be avoided insofar as specific               
          chemical structures are alleged to be prima facie obvious in view            
          of one another.  In re Grabiak, 769 F.2d 729, 732, 226 USPQ 870,             
          872 (Fed. Cir. 1985). Note also the court's comment in the                   
          decision of In re Rosselet, 347 F.2d 847, 851, 146 USPQ 183, 186             
          (CCPA 1965) that "We do not herein hold, impliedly or otherwise,             
          that any compound differing from the prior art solely by a                   
          hydroxy or methyl group is deemed prima facie obvious in view of             
          that art..."  Thus the obviousness of chemical compounds must be             
          decided on a case by case basis.                                             





                    On the basis of the record before us, we cannot sustain            
          the examiner's position and conclusion that the claimed compound             
          and the proffered compound of Rohrback are so closely related in             
          structure as to render the claimed compound prima facie obvious.             
          There are two leaps made by the examiner which are unsupported by            
          evidence. The first is that one of ordinary skill in the art                 
          would have made the selections proposed by the examiner for n, M,            
          X, Y and Z.  Cf. Merck Co., Inc. v. Biocraft Laboratories, Inc.              
          874 F.2d 804, 10 USPQ2d 1843 (Fed. Cir. 1989); and In re Susi,               

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