Appeal No. 94-2156 Application 07/888,366 the same -Trp-Gly-Trp-Cys- internal sequence (Trp has a unique codon) as the known 43 amino acid sequence of mature hevein (Ans., pp. 9-11), yet the fact that appellants’ claims are drawn to cDNA which encodes a novel 204 amino acid precursor is not considered to be a material distinction. We disagree. The examiner states (Ans., pp. 11-13, bridging para. (3)): While applicants urge that the actual gene expression product and encoding cDNA sequence are larger than the known hevein protein having only 43 amino acids, one of ordinary skill in the art in carrying out the method of Weissman . . . would have inherently or inevitably obtained the full-length cDNA sequence corresponding to the gene encoding the protein which included these 43 amino acids . . . . In our view, the examiner erroneously equates the requisite “likelihood of success” to inevitability. Rather, for obviousness under 35 U.S.C. § 103, persons having ordinary skill in the art would have had to have a reasonable expectation of success in view of the cited prior art. See In re O’Farrell, 853 F.2d at 904, 7 USPQ2d at 1681 (“For obviousness under § 103, all that is required is a reasonable expectation of success.”) The examiner predicts (Ans., p. 12, l. 12-17): - 9 -Page: Previous 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 NextLast modified: November 3, 2007