Ex parte DOWDLE - Page 4




          Appeal No. 95-0155                                                          
          Application No. 07/890,335                                                  


          D. Collen, "Synergism of Tissue-Type Plasminogen Activator                  
          (t-PA) and Single-Chain Urokinase-Type Plasminogen Activator                
          (scu-PA) on Clot Lysis In Vitro and a Mechanism for this                    
          Effect," 57 Thrombosis and Haemostasis no. 3, 373 (1987).                   
                                      THE ISSUE                                       
               As stated in the Examiner's Answer, page 2, section (4),               
          the previously entered rejections under 35 U.S.C. § 112, first              
          paragraph, and under 35 U.S.C. § 103 over the Reich et al.                  
          reference, have been withdrawn.                                             
               The sole issue on appeal is whether the examiner erred in              
          rejecting claims 69, 70, 72 through 78, 80 through 84, 87                   
          through 90 and 92 through 96 under 35 U.S.C. § 103 as                       
          unpatentable over European Patent Application 0 041 766.                    
                                    DELIBERATIONS                                     
               Our deliberations in this matter have included evaluation              
          and review of the following materials:  (1) the instant speci-              
          fication, including all of the claims on appeal; (2)                        
          applicant's Appeal Brief, the Reply Brief, and the                          
          Supplemental Reply Brief; (3) the Examiner's Answer; and (4)                
          the above-cited references relied on by the examiner.                       
               On consideration of the record, including the above-                   
          listed materials, we reverse the examiner's rejection under                 
          35 U.S.C. § 103.                                                            

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