Appeal No. 95-4847 Application No. 08/079,222 Disclosure of the invention thus far has contemplated the injection of bioprotective material 26 between the inflating balloon and the arterial wall. Another method . . . contemplates applying a thin sleeve of such material to the external surface of the LBA balloon. The thin sleeve is then transferred to the luminal surface as a result of heat and pressure (column 9, lines 19-26). From the above, it is our view that Spears would have suggested to one of ordinary skill in the art that fibrin in the form of a pre-formed film of drug-containing microspheres be placed on the external surface of the balloon element of an angioplasty catheter and placed in contact with the interior wall of a body lumen for the purpose of treating the wall. It is our further view that one of ordinary skill in the art would have found it obvious to coat the stents of Schatz with fibrin in place of the coatings disclosed in Schatz, suggestion being found in the explicit teachings of Schatz and Spears referred to above, which establish the desirability of (1) coating a stent with materials to be applied to the walls of the body lumen and (2) utilizing fibrin as such a material. We note here that the prior art teachings relied upon need not disclose the same advantage that the appellant alleges, for all that is required is that there is a reasonable suggestion 6Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007