Appeal No. 95-1641 Application No. 07/825,927 the examiner that the examples in the Yamauchi reference constitute “large scale” processes within the meaning of the claims. Even if we were to interpret “large scale” to mean “commercial-scale” as appears to be asserted by appellants (see Brief, page 16), our conclusion would remain the same since the Yamauchi reference suggests that its process can be employed on “a commercial scale”. See column 3, lines 32-33. Note also that appellants acknowledge the existence of “prior art large scale processes”. See Brief, page 13. In spite of the fact that the Yamauchi reference, a U.S. patent, is entitled to a statutory presumption of validity and that an enabling disclosure is a prerequisite to validity under 35 U.S.C. § 112, first paragraph (Cf. In re Spence, 261 F.2d 244, 246, 120 USPQ 82, 83 (CCPA 1958)), appellants take the position that the Yamauchi reference is not enabling with respect to a large scale process. In support of their position, appellants refer to page 4-21 of Perry’s Chemical Engineer’s Handbook (6th ed.), which is said to provide: It has been generally accepted that the design of a commercial-scale chemical reactor, which is the heart of a chemical plant, cannot be accomplished by 11Page: Previous 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 NextLast modified: November 3, 2007