Ex parte NURMI et al. - Page 11




          Appeal No. 95-1641                                                           
          Application No. 07/825,927                                                   


          the examiner that the examples in the Yamauchi reference                     
          constitute “large scale” processes within the meaning of the                 
          claims.  Even if we were to interpret  “large scale” to mean                 
          “commercial-scale” as appears to be asserted by appellants                   
          (see Brief, page 16), our conclusion would remain the same                   
          since the Yamauchi reference suggests that its process can be                
          employed on “a commercial scale”.   See column 3, lines 32-33.               
          Note also that appellants acknowledge the existence of “prior                
          art large scale processes”.  See Brief, page 13.                             
               In spite of the fact that the Yamauchi reference, a U.S.                
          patent, is entitled to a statutory presumption of validity and               
          that an enabling disclosure is a prerequisite to validity                    
          under 35 U.S.C. § 112, first paragraph (Cf. In re Spence, 261                
          F.2d 244, 246, 120 USPQ 82, 83 (CCPA 1958)), appellants take                 
          the position that the Yamauchi reference is not enabling with                
          respect to a large scale process.  In support of their                       
          position, appellants refer to page 4-21 of Perry’s Chemical                  
          Engineer’s Handbook (6th ed.), which is said to provide:                     
               It has been generally accepted that the design of a                     
               commercial-scale chemical reactor, which is the                         
               heart of a chemical plant, cannot be accomplished by                    


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