Appeal No. 95-1641 Application No. 07/825,927 a purely theoretical approach alone. See Brief, page 16. Appellants, however, have not supplied a copy of this document to support appellants’ position. Having considered appellants’ unsupported position, we are convinced that appellants have not met their burden of proof. In the first place, a mere attorney argument is insufficient to establish that the Yamauchi reference is not enabling with respect to a large scale process. See In re Pearson, 494 F.2d 1399, 1405, 181 USPQ 641, 646 (CCPA 1974) (an argument of counsel in a brief cannot take the place of evidence in the record). In the second place, the quote referred to by appellants does not indicate that Yamauchi’s crystallization process cannot be carried out in a “large-scale” or a “commercial-scale” based on the Yamauchi disclosure which includes more than a “purely theoretical approach”. In the third place, the quote referred to by appellants does not indicate that the design of a commercial-scale crystallizer cannot be accomplished by those skilled in the art particularly in view of the state of the art known at the time the application was filed. 12Page: Previous 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 NextLast modified: November 3, 2007