Appeal No. 1995-4851
Application 08/167,656
(Fed. Cir. 1992). The examiner must explain why the prior art
would have suggested to one of ordinary skill in the art the
desirability of the modification. See id. at 1266, 23 USPQ2d
at 1783-84.
Manzer’s desired product is asymmetric with respect to
fluorine (col. 2, lines 8-12), whereas Groppelli teaches that
his catalyst produces a compound which is symmetric as to
fluorine (col. 1, lines 35-46). In the Manzer declaration
(filed June 29, 1994; paper no. 24, page 4), Manzer states
that one of ordinary skill in the art would not conclude from
Groppelli’s disclosure that Groppelli’s catalyst would be
desirable for use in making Manzer’s less symmetric compounds.
In the declaration (page 5), Manzer points out that
Groppelli’s Table 1 shows that including zinc in the catalyst
greatly enhances the net yield of the more symmetric C F Cl
2 4 2
isomer, CF ClCF Cl, compared to the less symmetric isomer,
2 2
CF CFCl . The table also shows that when zinc is included in
3 2
the catalyst, the net yield of asymmetric CF CCl is a trace,
3 3
whereas when the catalyst does not contain zinc, the net
yields of that compound are 7.7-26%.
10
Page: Previous 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Next
Last modified: November 3, 2007