Appeal No. 1995-4851 Application 08/167,656 The examiner does not explain, and it is not apparent, why one of ordinary skill in the art, in light of the above- discussed teaching by Groppelli, would have had a “reasonable expectation of obtaining a similar result” (answer, page 6) as that obtained when the Manzer catalyst is used. Instead, it appears that Groppelli would have led one of ordinary skill in the art to expect that Groppelli’s catalyst, if used in the Manzer process, would produce symmetrical products rather than the asymmetric compounds desired by Manzer. The examiner argues that Manzer’s teaching, discussed above, wherein reaction variables can be controlled to minimize production of the trifluorochloroethane desired by appellants, would have suggested using closely related catalysts such as that disclosed by Groppelli (answer, page 6). This argument is not convincing. The examiner does not explain why, in view Groppelli’s indication that use of zinc in the catalyst causes the product to be symmetric rather than to be asymmetric as desired by Manzer, one of ordinary skill 11Page: Previous 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 NextLast modified: November 3, 2007